Design, Synthesis and Antibacterial Evaluation of Novel Fluoroquinolone and its Derivatives
نویسندگان
چکیده
منابع مشابه
Novel fluoroquinolone derivatives bearing N-thiomide linkage with 6-substituted-2-aminobenzothiazoles: Synthesis and antibacterial evaluation
a Institute of Pharmaceutical Sciences, Kurukshetra University, Kurukshetra 136 119, Haryana, India b Department of Pharmaceutical Chemistry, Rajendra Institute of Technology & Sciences, Sirsa 125 055, Haryana, India c Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Hamdard University, New Delhi 110 062, India d Department of Biochemistry, Kurukshetra University, Kurukshetra 136 11...
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A series of hydroxysemicarbazone derivatives of substituted diaryl ketones and acetophenones were synthesized and their structures were confirmed by analytical and spectroscopic methods including elemental analysis, infrared and nuclear magnetic resonance spectroscopy. The derivatives were prepared by a condensation reaction between N-hydroxysemicarbazide and substituted diaryl ketones or aceto...
متن کاملDesign, Synthesis, Molecular Docking, and Antibacterial Evaluation of Some Novel Flouroquinolone Derivatives as Potent Antibacterial Agent
OBJECTIVE Quinolone moiety is an important class of nitrogen containing heterocycles widely used as key building blocks for medicinal agents. It exhibits a wide spectrum of pharmacophores and has bactericidal, antiviral, antimalarial, and anticancer activities. In view of the reported antimicrobial activity of various fluoroquinolones, the importance of the C-7 substituents is that they exhibit...
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A series of hydroxysemicarbazone derivatives of substituted diaryl ketones and acetophenones were synthesized and their structures were confirmed by analytical and spectroscopic methods including elemental analysis, infrared and nuclear magnetic resonance spectroscopy. The derivatives were prepared by a condensation reaction between N-hydroxysemicarbazide and substituted diaryl ketones or aceto...
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ژورنال
عنوان ژورنال: Asian Journal of Chemistry
سال: 2014
ISSN: 0970-7077,0975-427X
DOI: 10.14233/ajchem.2014.15572